Lowered production of liver enzymes might indicate dysfunction of the liver. This article discusses the causes and symptoms of low liver enzymes. Liver helps get rid of toxic substances from the body.
It manufactures proteins which are important for prompt clotting of blood. It promotes the metabolism of medications and nutrients, vitamins, bile, and cholesterol. Liver helps manage glucose levels and procedure (and recycle) the waste products of hemoglobin (bilirubin) in blood.
The enzymes that are present in the liver help speed up the chemical reactions within the liver. Because of their existence, the liver has the ability to carry out a range of functions.
Can Liver Enzymes Be Lowered?
It is an important organ which helps in blood purification, detoxification, digestion, excretion, metabolic process and blood filtration.
Inadequate amount of liver enzymes may be a sign of liver disability or harmed liver cells which can impact liver function and the general health of the person seriously.
The following list consists of the different liver enzymes and the description of their typical values, together with the causes of what may be the factor behind low levels of each of these enzymes.
The following enzymes are necessary for typical liver functioning. Their decrease causes serious damage:
- Globulin. The protein globulin is produced in the liver and the body immune system. Albumin and globulin are the primary proteins present in the bloodstream. The normal overall protein levels, which are figured out by computing the albumin and globulin levels, ranges between 6.0 to 8.3 grams per deciliter.
- Albumin. A crucial protein that is present in the blood is albumin, and this is produced by the liver. Badly harmed liver can not produce albumin. A blood test helps identify albumin levels in blood. Its regular range is 3.4 to 5.4 grams/deciliter.
- Bilirubin is a waste item of the red blood cells and is produced during their breakdown. Normal total bilirubin level varies in between 0.3 to 1.9 mg/dL. Low bilirubin levels are normally not of any major issue.
- Prothrombin. Liver produces prothrombin, a kind of protein which promotes prompt clotting of blood. A prothrombin time test helps measure the time required for a person’s blood to clot. The typical variety for this test, if you are not taking any blood thinning medications, is in between INR of 0.8 to 1.1, where INR stands for International Normalized Ratio. Low levels of this enzyme will give you a result above INR 1.1, which implies that your blood is taking longer than typical to embolisms.
- Alanine Aminotransferase (ALT) is primarily present in the liver only and helps in metabolizing the protein present in the body. The regular ALT levels vary is 10 to 40 worldwide systems per liter (IU/L).
- Aspartate Aminotransferase (AST) exists in the liver, heart, and in other tissues of the body. The normal blood AST variety is 10 to 34 IU/L. ALT and AST are used to metabolize amino acids and make proteins. Liver dysfunction can change the production of AST.
- Alkaline Phosphatase (ALP) exists in all the tissues of the body. Nevertheless, its large amounts are discovered in the bones, liver, and bile ducts. The regular series of ALP is 44 to 147 IU/L.
- Lactate Dehydrogenase (LDH) or LD enzyme is found in the liver, and its normal variety is in between 105 to 333 IU/L. Generally, elevated levels of this enzyme are a cause of issue.
- Gamma-glutamyltranspeptidase (GGT). This enzyme is discovered in the blood. The normal values range from 0 to 51 global systems per liter (IU/L).
What Causes Low Liver Enzymes?
Various enzymes present in the liver help it to carry out the numerous metabolic functions usually. Reduced liver enzymes are an indication of liver damage which impacts the liver function dramatically.
Causes for low liver enzymes are determined by liver function tests, ultrasound, CT scan, MRI, biopsy, and so on.
Likewise, symptoms such as– jaundice, abdominal discomfort and pain, dark urine, tarry stools, bad breath, fever, minimized appetite and weakness help detect.
- liver illness such as– cirrhosis and fatty liver disease
- liver hemangiomas
- severe diarrhoea
- iron shortage
- fever and infections
- protein deficiency
- severe burns
- kidney illness
- too much usage of fat.
Low Liver Enzymes Symptoms
Symptoms that indicate liver disorders might vary from individual to individual. Mostly, there are no symptoms observed, or maybe they are so mild in nature, that most people do not even learn that they have low liver enzymes. A few of the symptoms that might or may not be seen in this condition are listed as under.
- abdominal swelling, bloating, vomiting, queasiness, weight loss
- tenderness in abdominal area in the region of the liver
- anorexia nervosa
- enlarged spleen.
Low Liver Enzymes Treatment
A series of liver function tests (LFTs: blood tests) and other tests including the ultrasound, CT scan, MRI, biopsy, and so on, help learn the enzyme that lack the body.
The test results help the doctors detect and chalk out the possible causes behind the same. Medical professionals might prescribe medicines to treat the particular underlying cause. But patients need to make some lifestyle changes, too.
A high-fiber diet that is low in ‘calories and hydrogenated fats’ can prove to be useful for individuals detected with liver problems. Don’t consume alcohol (alcohol is harmful for health)!
Preventing high-glycemic foods, controlling illness such as diabetes with timely medication, cholesterol, and triglyceride levels through diet, routine workout, and use of ‘required and enough’ medication is similarly crucial.
Liver illness are called ‘quiet killers’ as they do not show any symptoms in the early stages, so make certain you obtain inspected at routine periods, specifically if you have a family history of the same.
Specialists state the most essential element of the treatment of a liver condition is a lifestyle overhaul. An ideal diet strategy designed by a nutritionist is essential.
A high fiber, low fat diet, removal of processed foods, adequate workout and optimal stress management is vital. Alongside, physicians recommend drugs that help re-establish normal liver function.
Good luck! Have a nice weekend!